Article
Novel variant of the P2X2 ATP receptor from the guinea pig organ of Corti.
Hearing research - 1 Jul 1998
Parker M S, Larroque M L, Campbell J M, Bobbin R P, Deininger P L
Abstract excerpt
ATP functions as a neurotransmitter and a neuromodulator in various tissues by acting on metabotropic (P2Y) and ionotropic (P2X) receptors. Evidence suggests that ATP activates P2X receptors on several cell types in the organ of Corti of guinea pig including outer hair cells (OHCs), Deiters' cells, Hensen's cells, pillar cells and inner hair cells (IHCs). Determining the sequence and structure of P2X receptors in...
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