Article
Loss of cerebum function ventralizes the zebrafish embryo.
Development (Cambridge, England) - 1 Apr 1997
Fisher S, Amacher S L, Halpern M E
Abstract excerpt
Recent studies implicate ventrally derived signals, in addition to dorsal ones emanating from the organizer, in patterning the vertebrate gastrula. We have identified five overlapping deficiencies that uncover the zebrafish cerebum locus and dramatically alter dorsal-ventral polarity at gastrulation. Consistent with the properties of experimentally ventralized amphibian embryos, cerebum mutants exhibit reduced...
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