Article
Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes.
Development (Cambridge, England) - 1 Dec 1996
Mullins M C, Hammerschmidt M, Kane D A, Odenthal J, Brand M, van Eeden F J, Furutani-Seiki M, Granato M, Haffter P, Heisenberg C P, Jiang Y J, Kelsh R N, Nüsslein-Volhard C
Abstract excerpt
We identified 6 genes that are essential for specifying ventral regions of the early zebrafish embryo. Mutations in these genes cause an expansion of structures normally derived from dorsal-lateral regions of the blastula at the expense of ventrally derived structures. A series of phenotypes of varied strengths is observed with different alleles of these mutants. The weakest phenotype is a reduction in the...
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