Article
Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish.
Development (Cambridge, England) - 1 Dec 1996
Solnica-Krezel L, Stemple D L, Mountcastle-Shah E, Rangini Z, Neuhauss S C, Malicki J, Schier A F, Stainier D Y, Zwartkruis F, Abdelilah S, Driever W
Abstract excerpt
One of the major challenges of developmental biology is understanding the inductive and morphogenetic processes that shape the vertebrate embryo. In a large-scale genetic screen for zygotic effect, embryonic lethal mutations in zebrafish we have identified 25 mutations that affect specification of cell fates and/or cellular rearrangements during gastrulation. These mutations define at least 14 complementation...
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