Article
Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish.
Development (Cambridge, England) - 1 Dec 1996
Solnica-Krezel L, Stemple D L, Mountcastle-Shah E, Rangini Z, Neuhauss S C, Malicki J, Schier A F, Stainier D Y, Zwartkruis F, Abdelilah S, Driever W
Abstract excerpt
One of the major challenges of developmental biology is understanding the inductive and morphogenetic processes that shape the vertebrate embryo. In a large-scale genetic screen for zygotic effect, embryonic lethal mutations in zebrafish we have identified 25 mutations that affect specification o...
Topics
- Animals
- Cell Survival
- DNA Mutational Analysis
- Gastrula
- Gene Expression Regulation, Developmental
- Genetic Complementation Test
- Mutagenesis
- Phenotype
- Zebrafish