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Article

LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

Cell - 21 Mar 1997

Riese J, Yu X, Munnerlyn A, Eresh S, Hsu S C, Grosschedl R, Bienz M

Abstract excerpt

wingless and decapentaplegic signal during endoderm induction in Drosophila to regulate expression of the homeotic gene Ultrabithorax. Here, we define a minimal wingless response sequence in the midgut enhancer of Ultrabithorax. We show that this sequence is recognized by the murine transcription factor LEF-1 (lymphocyte enhancer binding factor 1) in a ternary complex with armadillo protein, the cytoplasmic...

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PMID: 9118221
DOI: 10.1016/s0092-8674(00)81924-8

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