Article
Suggestive linkages between markers on human 1p32-p22 and body fat and insulin levels in the Quebec Family Study.
Obesity research - 1 Mar 1997
Chagnon Y C, Pérusse L, Lamothe M, Chagnon M, Nadeau A, Dionne F T, Gagnon J, Chung W K, Leibel R L, Bouchard C
Abstract excerpt
A single-gene rodent mutation (diabetes) and a quantitative trait locus (dietary obese 1) mapped to the mid portion of mouse chromosome 4 have been related to obesity and/or insulin levels. Synteny relationships place their putative human homologs on 1p31 and 1p35-p31, respectively. In 137 sibships of adult brothers and sisters from the Québec Family Study, genetic linkages between seven microsatellite markers...
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