Article
Suggestive linkages between markers on human 1p32-p22 and body fat and insulin levels in the Quebec Family Study.
Obesity research - 1 Mar 1997
Chagnon Y C, Pérusse L, Lamothe M, Chagnon M, Nadeau A, Dionne F T, Gagnon J, Chung W K, Leibel R L, Bouchard C
Abstract excerpt
A single-gene rodent mutation (diabetes) and a quantitative trait locus (dietary obese 1) mapped to the mid portion of mouse chromosome 4 have been related to obesity and/or insulin levels. Synteny relationships place their putative human homologs on 1p31 and 1p35-p31, respectively. In 137 sibshi...
Topics
- Adolescent
- Adult
- Aged
- Animals
- Body Composition
- Body Mass Index
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Diabetes Mellitus
- Disease Models, Animal
- Family Health
- Female
- Genetic Linkage
- Humans
- Insulin
- Insulin Resistance
