Article
Fasting insulin and obesity-related phenotypes are linked to chromosome 2p: the Strong Heart Family Study.
Diabetes - 1 Jun 2006
Diego Vincent P, Göring Harald H H, Cole Shelley A, Almasy Laura, Dyer Thomas D, Blangero John, Duggirala Ravindranath, Laston Sandra, Wenger Charlotte, Cantu Teresa, Dyke Bennett, North Kari, Schurr Theodore, Best Lyle G, Devereux Richard B, Fabsitz Richard R, Howard Barbara V, MacCluer Jean W
Abstract excerpt
To localize quantitative trait loci for insulin metabolism and obesity, genome scans/linkage analyses were performed on >900 members of 32 extended families participating in phase 3 of the Strong Heart Study, an investigation of the genetic and environmental determinants of cardiovascular disease in American-Indian populations from Arizona, Oklahoma, and North and South Dakota. Linkage analyses of fasting insulin...
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