Article
Screening for the mitochondrial DNA A3243G mutation in children with insulin-dependent diabetes mellitus.
Metabolism: clinical and experimental - 1 Apr 1997
Abad M M, Cotter P D, Fodor F H, Larson S, Ginsberg-Fellner F, Desnick R J, Abdenur J E
Abstract excerpt
Since recent studies demonstrated the occurrence of the mitochondrial DNA (mtDNA) mutation A3243G in patients with adult-onset diabetes, an investigation was undertaken to determine the frequency of this mutation in a pediatric population with insulin-dependent diabetes mellitus (IDDM). DNA was extracted from peripheral blood of 270 pediatric patients with IDDM. The presence of the mtDNA A3243G mutation was...
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