Article
Molecular analysis of diabetes mellitus-associated A3243G mitochondrial DNA mutation in Taiwanese cases.
Diabetes research and clinical practice - 1 Dec 2001
Liou C W, Huang C C, Wei Y H
Abstract excerpt
Investigation of the clinical manifestations of MELAS-specific A3243G mitochondrial DNA (mtDNA) point mutation has suggested that the A3243G mutation of mtDNA can cause certain subtypes of diabetes mellitus (DM) and contributes about 0.15% of the overall incidence of diabetes. However, a relationship between the diabetic syndrome and the proportion of mutant mtDNA in affected tissues remains unclear. In this...
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