Article
Involvement of the RE V3 gene in the methylated base-excision repair system. Co-operation of two DNA polymerases, delta and Rev3p, in the repair of MMS-induced lesions in the DNA of Saccharomyces cerevisiae.
Current genetics - 1 Apr 1997
Halas A, Baranowska H, Policińska Z, Jachymczyk W J
Abstract excerpt
The ability of four yeast DNA polymerase mutant strains to carry out the repair of DNA treated with MMS was studied. Mutation in DNA polymerase Rev3, as well as the already known mutation in the catalytic subunit of DNA polymerase delta, were both found to lead to the accumulation of single-stran...
Topics
- DNA Damage
- DNA Methylation
- DNA Polymerase II
- DNA Polymerase III
- DNA Polymerase beta
- DNA Repair
- DNA, Single-Stranded
- DNA-Directed DNA Polymerase
- Fungal Proteins
- Glycoproteins
- Methyl Methanesulfonate
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Temperature