Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic (Co)variation for life span in rhabditid nematodes: role of mutation, selection, and history.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Nov 2009

Joyner-Matos Joanna, Upadhyay Ambuj, Salomon Matthew P, Grigaltchik Veronica, Baer Charles F

Abstract excerpt

The evolutionary mechanisms maintaining genetic variation in life span, particularly post-reproductive life span, are poorly understood. We characterized the effects of spontaneous mutations on life span in the rhabditid nematodes Caenorhabditis elegans and C. briggsae and standing genetic variance for life span and correlation of life span with fitness in C. briggsae. Mutations decreased mean life span, a...

Topics

Aging
Animals
Caenorhabditis
Caenorhabditis elegans
Genetic Variation
Mortality
Mutation
Selection, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19671885
DOI: 10.1093/gerona/glp112
PMCID: PMC2759666

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic (Co)variation for life span in rhabditid nematodes: role of mutation, selection, and history.PMID 19671885Read ↗

Spontaneous mutational and standing genetic (co)variation at dinucleotide microsatellites in Caenorhabditis briggsae and Caenorhabditis elegans.Semantic proximity Read ↗

Comparing mutational and standing genetic variability for fitness and size in Caenorhabditis briggsae and C. elegans.Semantic proximity Read ↗

Comparative evolutionary genetics of spontaneous mutations affecting fitness in rhabditid nematodes.Semantic proximity Read ↗

Mutational bias for body size in rhabditid nematodes.Semantic proximity Read ↗

Cumulative effects of spontaneous mutations for fitness in Caenorhabditis: role of genotype, environment and stress.Semantic proximity Read ↗

A recent global selective sweep on the age-1 phosphatidylinositol 3-OH kinase regulator of the insulin-like signaling pathway within Caenorhabditis remanei.Semantic proximity Read ↗

Muller's Ratchet and compensatory mutation in Caenorhabditis briggsae mitochondrial genome evolution.Semantic proximity Read ↗

Evidence for a genetic basis of aging in two wild vertebrate populations.Semantic proximity Read ↗

Temperature, stress and spontaneous mutation in Caenorhabditis briggsae and Caenorhabditis elegans.Semantic proximity Read ↗

Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans.Semantic proximity Read ↗

Natural variation for lifespan and stress response in the nematode Caenorhabditis remanei.Semantic proximity Read ↗

Rapid decline in fitness of mutation accumulation lines of gonochoristic (outcrossing) Caenorhabditis nematodes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.