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Article

Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegans.

Genetics - 1 Mar 2004

Estes Suzanne, Phillips Patrick C, Denver Dee R, Thomas W Kelley, Lynch Michael

Abstract excerpt

The consequences of mutation for population-genetic and evolutionary processes depend on the rate and, especially, the frequency distribution of mutational effects on fitness. We sought to approximate the form of the distribution of mutational effects by conducting divergence experiments in which lines of a DNA repair-deficient strain of Caenorhabditis elegans, msh-2, were maintained at a range of population...

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Source

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Identifiers

PMID: 15082546
DOI: 10.1534/genetics.166.3.1269
PMCID: PMC1470770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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