Article
Antibacterial activities of grepafloxacin, ciprofloxacin, ofloxacin and fleroxacin.
Journal of chemotherapy (Florence, Italy) - 1 Feb 1997
Barry A L, Fuchs P C
Abstract excerpt
Grepafloxacin (OPC-17116) and three other fluoroquinolones were tested against 461 bacterial isolates representing 44 species. Grepafloxacin was superior to ciprofloxacin, ofloxacin and fleroxacin in its activity against the Gram-positive cocci, including staphylococci, pneumococci and hemolytic streptococci. Attempts to select grepafloxacin-resistant mutants from a methicillin-resistant Staphylococcus aureus...
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