Article
Autoimmune diabetes: the role of T cells, MHC molecules and autoantigens.
Autoimmunity - 1 Jan 1998
Durinovic-Belló I
Abstract excerpt
Type 1 diabetes (IDDM) is a T cell mediated autoimmune disease which in part is determined genetically by its association with major histocompatibility complex (MHC) class II alleles. The major role of MHC molecules is the regulation of immune responses through the presentation of peptide epitope...
Topics
- Alleles
- Animals
- Autoantigens
- Autoimmunity
- Child
- Diabetes Mellitus, Type 1
- Epitopes, T-Lymphocyte
- Glutamate Decarboxylase
- Humans
- Immunity, Cellular
- Insulin
- Islets of Langerhans
- Major Histocompatibility Complex
- Membrane Proteins
- Mice
- Models, Biological
- Protein Tyrosine Phosphatase, Non-Receptor Type 1
- Protein Tyrosine Phosphatases
