Article
The Trp(64)Arg polymorphism of the beta(3)-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: a longitudinal analysis.
The Journal of clinical endocrinology and metabolism - 1 Dec 2003
Matsushita Yumi, Yokoyama Tetsuji, Yoshiike Nobuo, Matsumura Yasuhiro, Date Chigusa, Kawahara Kazuo, Tanaka Heizo
Abstract excerpt
The beta(3)-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. Although many studies have examined the relationship between the Trp(64)Arg mutation of ADRB3 and obesity, the results have been inconsistent. We examined the cross-sectional relationship of ADRB3 variants with indexes of obesity,...
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