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Article

An alpha-helical minimal binding domain within the H3 domain of syntaxin is required for SNAP-25 binding.

Biochemistry - 8 Apr 1997

Zhong P, Chen Y A, Tam D, Chung D, Scheller R H, Miljanich G P

Abstract excerpt

The interaction between the proteins syntaxin 1A and SNAP-25 is a key step in synaptic vesicle docking and fusion. To define the SNAP-25 binding domain on syntaxin, we have prepared peptides that span the syntaxin H3 domain (residues 191-266), the region previously shown to be important for binding to SNAP-25, and then determined the affinities of these peptides for binding to SNAP-25. A minimal binding domain...

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Source

Identifiers

PMID: 9100028
DOI: 10.1021/bi9625408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An alpha-helical minimal binding domain within the H3 domain of syntaxin is required for SNAP-25 binding.PMID 9100028Read ↗

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