Article
Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis.
BMC biology - 8 Aug 2012
Klöpper Tobias H, Kienle Nickias, Fasshauer Dirk, Munro Sean
Abstract excerpt
BACKGROUND: Membrane-bound organelles are a defining feature of eukaryotic cells, and play a central role in most of their fundamental processes. The Rab G proteins are the single largest family of proteins that participate in the traffic between organelles, with 66 Rabs encoded in the human genome. Rabs direct the organelle-specific recruitment of vesicle tethering factors, motor proteins, and regulators of...
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