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Marked amplification and diversification of products of ras genes from rat brain, Rab GTPases, in the ciliates Tetrahymena thermophila and Paramecium tetraurelia.

The Journal of eukaryotic microbiology - 1 Jan 2000

Saito-Nakano Yumiko, Nakahara Tohru, Nakano Kentaro, Nozaki Tomoyoshi, Numata Osamu

Abstract excerpt

Small GTPase Rab (products of ras genes from rat brain) is a widely conserved molecular switch among eukaryotes and regulates membrane trafficking pathways. It is generally considered that the number of Rab encoded in the genome correlates with multicellularity; however, we found that unicellular ciliates Tetrahymena thermophila (Tt) and Paramecium tetraurelia (Pt) possess many more Rab genes in their genome than...

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PMID: 20738463
DOI: 10.1111/j.1550-7408.2010.00503.x

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