Article
Electrostatic effects in homeodomain-DNA interactions.
Journal of molecular biology - 28 Mar 1997
Fogolari F, Elcock A H, Esposito G, Viglino P, Briggs J M, McCammon J A
Abstract excerpt
We report here an investigation of the role of electrostatics in homeodomain-DNA interactions using techniques based around the use of the Poisson-Boltzmann equation. In the present case such a study is of particular interest, since in contrast to other proteins previously studied with this metho...
Topics
- Amino Acid Sequence
- Base Sequence
- Chemical Phenomena
- Chemistry, Physical
- DNA
- DNA-Binding Proteins
- Electrochemistry
- Homeodomain Proteins
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Binding
- Protein Conformation
- Salts
- Static Electricity
- Temperature
- Thermodynamics
