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Article

Electrostatic effects in homeodomain-DNA interactions.

Journal of molecular biology - 28 Mar 1997

Fogolari F, Elcock A H, Esposito G, Viglino P, Briggs J M, McCammon J A

Abstract excerpt

We report here an investigation of the role of electrostatics in homeodomain-DNA interactions using techniques based around the use of the Poisson-Boltzmann equation. In the present case such a study is of particular interest, since in contrast to other proteins previously studied with this method, the homeodomain is a small, highly charged protein that forms extensive ion pairs upon binding DNA. We have...

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Identifiers

PMID: 9096232
DOI: 10.1006/jmbi.1996.0842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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