The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability.

doi:10.1093/protein/7.11.1365

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Article

The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability.

Protein engineering - 1 Nov 1994

Zhou N E, Kay C M, Hodges R S

Abstract excerpt

The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability has been quantitated using de novo designed synthetic coiled-coils. The synthesized model coiled-coil (EK), denoted by amino acid residues in positions e and g, which contains only interhelical ionic...

Topics

Amino Acid Sequence
Chemical Phenomena
Chemistry, Physical
Circular Dichroism
Ions
Leucine Zippers
Models, Molecular
Molecular Sequence Data
Mutation
Peptides
Protein Denaturation
Protein Folding
Protein Structure, Tertiary
Urea

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