Article
The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability.
Protein engineering - 1 Nov 1994
Zhou N E, Kay C M, Hodges R S
Abstract excerpt
The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability has been quantitated using de novo designed synthetic coiled-coils. The synthesized model coiled-coil (EK), denoted by amino acid residues in positions e and g, which contains only interhelical ionic interactions without any possible (i, i + 3) and (i, i + 4) intrahelical ionic interaction, consists of two identical...
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