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Article

The human immunodeficiency virus type 1 encapsidation site is a multipartite RNA element composed of functional hairpin structures

1 May 1996

Abstract excerpt

We analyzed the leader region of human immunodeficiency virus type 1 (HIV-1) RNA to decipher the nature of the cis-acting E/psi element required for encapsidation of viral RNA into virus particles. Our data indicate that, for RNA encapsidation, there are at least two functional subregions in the leader region. One subregion is located at a position immediately proximal to the major splice donor, and the second is...

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PMID: 8627772
DOI: 10.1128/jvi.70.5.2963-2973.1996

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