Article
Influence of GSTM1 and GSTT1 polymorphisms on the frequency of chromosome aberrations in lymphocytes of smokers and pesticide-exposed greenhouse workers.
Mutation research - 17 Mar 1997
Scarpato R, Hirvonen A, Migliore L, Falck G, Norppa H
Abstract excerpt
The influence of polymorphic glutathione S-transferases mu (GSTM1) and theta (GSTT1) on the rate of chromosome aberrations (CA) in peripheral lymphocytes of 30 pesticide-exposed floriculturists and 32 control subjects was studied. Pesticide exposure was not associated with elevated frequencies of CA. Among cigarette smokers, a statistically significant (p = 0.026) increase in baseline CA frequencies was observed...
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