Article
Cytogenetic and molecular biomonitoring of a Portuguese population exposed to pesticides.
Mutagenesis - 1 Sept 2006
Costa Carla, Teixeira João P, Silva Susana, Roma-Torres Joana, Coelho Patrícia, Gaspar Jorge, Alves Maria, Laffon Blanca, Rueff José, Mayan Olga
Abstract excerpt
Widespread use of pesticides in agriculture represents a threat not only to the environment but also to human populations exposed to them. Many of these compounds are capable of inducing mutations in DNA and lead to several diseases including cancer. In the present study, cytogenetic damage in peripheral lymphocytes from 33 farmers of Oporto district (Portugal) exposed to pesticides was evaluated by means of...
Topics
- Adult
- Case-Control Studies
- Chromosome Aberrations
- Chromosome Breakage
- Cytochrome P-450 CYP2E1
- DNA Damage
- Epoxide Hydrolases
- Female
- Genotype
- Glutathione S-Transferase pi