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Article

Occupational Exposure to Pesticides in Tobacco Fields: The Integrated Evaluation of Nutritional Intake and Susceptibility on Genomic and Epigenetic Instability.

Oxidative medicine and cellular longevity - 1 Jan 2018

Kahl Vivian F Silva, Dhillon Varinderpal, Fenech Michael, de Souza Melissa Rosa, da Silva Fabiane Nitzke, Marroni Norma Anair Possa, Nunes Emilene Arusievicz, Cerchiaro Giselle, Pedron Tatiana, Batista Bruno Lemos, Cappetta Mónica, Mártinez-López Wilner, Simon Daniel, da Silva Juliana

Abstract excerpt

Pesticides used at tobacco fields are associated with genomic instability, which is proposed to be sensitive to nutritional intake and may also induce epigenetic changes. We evaluated the effect of dietary intake and genetic susceptibility polymorphisms in MTHFR (rs1801133) and TERT (rs2736100) genes on genomic and epigenetic instability in tobacco farmers. Farmers, when compared to a nonexposed group, showed...

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Source

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Identifiers

PMID: 29967663
DOI: 10.1155/2018/7017423
PMCID: PMC6009020

Genes

MTHFR
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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