Article
Phenotypic Aging and Sexual Dimorphism in C57BL/6J, SAMR1, and SAMP8 Mice: A Comparative Study.
Mediators of inflammation - 1 Jan 2026
Queiroz Luiz Adriano Damasceno, Fontes Renata Spalutto, Oliveira Mariana de Araujo, Pantoja Kamilla Costa, Assis Josiane Betim, Tavares Ywa Perpetuo Socorro Toda, Barros Rafael Dos Santos, Turato Walter Miguel, Sá-Nunes Anderson, Moustaid-Moussa Naima, Rodrigues Stephen Fernandes, Martins Joilson O
Abstract excerpt
Aging research increasingly relies on animal models to study the multifactorial processes of senescence. This study aimed to compare the physiological and metabolic parameters of C57BL/6J mice, a reference strain for biomedical research, with two strains commonly used to assess senescence: senescence-accelerated resistant 1 (SAMR1) and senescence-accelerated prone 8 (SAMP8) mice, over a 1-year period, in order to...
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