Article
Internet resources for phenotyping engineered rodents.
ILAR journal - 1 Jan 2006
Bolon Brad
Abstract excerpt
Genetically engineered mice (GEM) and rats (GER) have emerged as the main mammalian models for investigating normal (physiological, or "health") and abnormal (patho-logical, or "disease") mechanisms. Regardless of the genetic manipulation, novel GEM and GER must undergo meticulous genotypic and phenotypic analyses before it is possible to predict the significance of the engineered gene with re-spect to health and...
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