Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.

doi:10.1161/01.hyp.24.1.63

Article

Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.

1 Jul 1994

Abstract excerpt

We conducted the present study to determine whether the angiotensin II type I receptor (AT1) gene might be implicated in human essential hypertension by using case-control and linkage studies. The entire coding and 3' untranslated regions of the AT1 receptor gene (2.2 kb) were amplified by polymerase chain reaction and submitted to single-strand conformation polymorphism in 60 hypertensive subjects with a...

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