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Article

Arginine506 to glutamin mutation in the factor V gene in infancy and childhood: evidence of fibrinolytic impairment.

European journal of pediatrics - 1 Mar 1997

Nowak-Göttl U, Vielhaber H, Grohmann J, Schneppenheim R, Koch H G

Abstract excerpt

UNLABELLED: Resistance to activated protein C (APCR), in the majority of cases due to arginine506 (Arg506) to glutamine (Gln) mutation in the factor V gene, has emerged as the most important hereditary cause of venous thrombo-embolism. To determine to what extent this relatively common gene mutation influences the fibrinolytic system we investigated a population of APC resistant children (n = 65) in comparison...

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Identifiers

PMID: 9083758
DOI: 10.1007/s004310050581

Genes

APC

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Arginine506 to glutamin mutation in the factor V gene in infancy and childhood: evidence of fibrinolytic impairment.PMID 9083758Read ↗

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