Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the effect of local interactions on protein stability.

Folding & design - 1 Jan 1996

Muñoz V, Cronet P, López-Hernández E, Serrano L

Abstract excerpt

BACKGROUND: Protein stability appears to be governed by non-covalent interactions. These can be local (between residues close in sequence) or non-local (medium-range and long-range interactions). The specific role of local interactions is controversial. Statistical mechanics arguments point out that local interactions must be weak in stable folded proteins. However, site-directed mutagenesis has revealed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kinetics

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Mutagenesis, Site-Directed

Share to Mutation

Source

Identifiers

PMID: 9079379
DOI: 10.1016/s1359-0278(96)00029-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the effect of local interactions on protein stability.PMID 9079379Read ↗

Folding kinetics of Che Y mutants with enhanced native alpha-helix propensities.Semantic proximity Read ↗

Protein stability prediction: a Poisson-Boltzmann approach.Semantic proximity Read ↗

Importance of surrounding residues for protein stability of partially buried mutations.Semantic proximity Read ↗

Protein stability: computation, sequence statistics, and new experimental methods.Semantic proximity Read ↗

Review of predicting protein stability changes upon variations.Semantic proximity Read ↗

Protein stability: still an unsolved problem.Semantic proximity Read ↗

The stability effects of protein mutations appear to be universally distributed.Semantic proximity Read ↗

A tale of two secondary structure elements: when a beta-hairpin becomes an alpha-helix.Semantic proximity Read ↗

Predicting the stability of mutant proteins by computational approaches: an overview.Semantic proximity Read ↗

Fine structure analysis of a protein folding transition state; distinguishing between hydrophobic stabilization and specific packing.Semantic proximity Read ↗

The denatured state (the other half of the folding equation) and its role in protein stability.Semantic proximity Read ↗

Modeling the effects of mutations on the denatured states of proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.