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Article

The stability effects of protein mutations appear to be universally distributed.

Journal of molecular biology - 22 Jun 2007

Tokuriki Nobuhiko, Stricher Francois, Schymkowitz Joost, Serrano Luis, Tawfik Dan S

Abstract excerpt

How the thermodynamic stability effects of protein mutations (DeltaDeltaG) are distributed is a fundamental property related to the architecture, tolerance to mutations (mutational robustness), and evolutionary history of proteins. The stability effects of mutations also dictate the rate and dyna...

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Identifiers

PMID: 17482644
DOI: 10.1016/j.jmb.2007.03.069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17482644-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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