Folding kinetics of Che Y mutants with enhanced native alpha-helix propensities.

doi:10.1006/jmbi.1996.0793

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Article

Folding kinetics of Che Y mutants with enhanced native alpha-helix propensities.

Journal of molecular biology - 28 Feb 1997

López-Hernández E, Cronet P, Serrano L, Muñoz V

Abstract excerpt

In this work we study the folding kinetics of Che Y mutants in which the helical propensity of each of its five alpha-helices has been greatly enhanced by local interactions (between residues close in sequence). This constitutes an experimental test on the role of local interactions in protein fo...

Topics

Bacterial Proteins
Escherichia coli
Kinetics
Membrane Proteins
Methyl-Accepting Chemotaxis Proteins
Mutation
Protein Folding
Thermodynamics

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