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Article

Apoptosis is increased in a model of diabetes-impaired wound healing in genetically diabetic mice.

The international journal of biochemistry & cell biology - 1 Jan 1997

Darby I A, Bisucci T, Hewitson T D, MacLellan D G

Abstract excerpt

Impaired wound healing is a common complication of diabetes mellitus. The underlying pathophysiology of diabetes-impaired healing is poorly understood. In the present study we have compared cell proliferation rates, apoptosis (programmed cell death), the myofibroblast marker alpha-smooth muscle actin and procollagen I mRNA expression, between diabetic and control mice. Full-thickness skin wounds were made in...

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Identifiers

PMID: 9076954
DOI: 10.1016/s1357-2725(96)00131-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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