Article
Association of the DD genotype and development of Japanese type 2 diabetic nephropathy.
Clinical nephrology - 1 Dec 2001
Gohda T, Makita Y, Shike T, Kobayashi M, Funabiki K, Haneda M, Kikkawa R, Watanabe T, Baba T, Yoshida H, Tomino Y
Abstract excerpt
We determined the insertion/deletion (I/D) polymorphism of the angiotensin-coverting enzyme (ACE) gene in a multicenter trial of ethnically homogeneous Japanese type 2 diabetes mellitus (DM) patients. All patients (n = 748) were divided into 5 groups as follows: group I (normoalbuminuric patients), group II (microalbuminuric patients), group III (overt albuminuric patients with serum creatinine (s-Cr) levels of...
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