Mutation of the tumor suppressor gene p53 in human prostate and bladder cancers--investigation by temperature gradient gel electrophoresis (TGGE).

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Article

Mutation of the tumor suppressor gene p53 in human prostate and bladder cancers--investigation by temperature gradient gel electrophoresis (TGGE).

The Journal of urology - 1 Mar 1997

Schlechte H H, Schnorr D, Löning T, Rudolph B D, Pohrt U M, Loening S A

Abstract excerpt

PURPOSE: To test the value of a recently developed screening method for the detection of p53 mutations in prostate and bladder cancers. MATERIALS AND METHODS: Tumor tissue from 24 prostate cancers and 27 bladder cancers were evaluated. DNA of the critical p53 exons 5-8 were amplified and run on h...

Topics

Adolescent
Aged
Aged, 80 and over
DNA Mutational Analysis
Electrophoresis
Exons
Genes, p53
Humans
Male
Middle Aged
Mutation
Neoplasm Staging
Prostatic Neoplasms
Temperature
Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9072541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9072541-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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