Article
Hitchhiking effect of a beneficial mutation spreading in a subdivided population.
Genetics - 1 Sept 2011
Kim Yuseob, Maruki Takahiro
Abstract excerpt
A central problem in population genetics is to detect and analyze positive natural selection by which beneficial mutations are driven to fixation. The hitchhiking effect of a rapidly spreading beneficial mutation, which results in local removal of standing genetic variation, allows such an analysis using DNA sequence polymorphism. However, the current mathematical theory that predicts the pattern of genetic...
Topics
- Algorithms
- Alleles
- Evolution, Molecular
- Genetics, Population
- Genotype
- Models, Genetic
- Mutation
- Selection, Genetic