Article
Inhibition of cell growth by overexpression of the ZPK gene.
Biochemical and biophysical research communications - 3 Feb 1997
Bergeron P, Douziech M, Daigle N, Blouin R
Abstract excerpt
ZPK is a recently described serine/threonine protein kinase that is thought to be involved in the regulation of cell proliferation and differentiation. To directly determine whether ZPK exhibits any effect on cell growth, NIH 3T3 fibroblasts were transfected with an expression vector harboring the murine ZPK cDNA. Stable expression of this construct led to a dramatic reduction in the proliferative capacity of...
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