Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Introduction of a myc reporter tag to improve the quality of mutation detection using the protein truncation test.

Human mutation - 1 Jan 1997

Rowan A J, Bodmer W F

Abstract excerpt

The protein truncation test is a useful method for identifying frameshift and nonsense mutations. The interpretation of real results is often made difficult by the presence of internally translated protein products and other nonspecific bands. To overcome these problems, the technique has been modified to include a myc reporter tag in the 5' primer used to amplify the genomic region of interest. The myc tag is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Base Sequence
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Share to Transcription, Genetic

Source

Identifiers

PMID: 9067758
DOI: 10.1002/(SICI)1098-1004(1997)9:2<172::AID-HUMU10>3.0.CO;2-#

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Introduction of a myc reporter tag to improve the quality of mutation detection using the protein truncation test.PMID 9067758Read ↗

Protein truncation test.Semantic proximity Read ↗

The protein truncation test in mutation detection and molecular diagnosis.Semantic proximity Read ↗

The protein truncation test: A review.Semantic proximity Read ↗

A complete protein truncation test for BRCA1 and BRCA2.Semantic proximity Read ↗

Enhanced sensitivity of a modified protein truncation test for exons 1-14 of the adenomatous polyposis coli gene.Semantic proximity Read ↗

Application of the protein truncation test (PTT) for the detection of tuberculosis sclerosis complex type 1 and 2 (TSC1 and TSC2) mutations.Semantic proximity Read ↗

Detection of NF1 mutations utilizing the protein truncation test (PTT).Semantic proximity Read ↗

Screening for unknown mutations by a bioluminescent protein truncation test with homogeneous detection.Semantic proximity Read ↗

In vitro transcription/translation analysis for the identification of translation-terminating mutations.Semantic proximity Read ↗

Two cat expression vectors for cloning and generation of 3'- and 5'-deletion mutants.Semantic proximity Read ↗

An ELISA-based high throughput protein truncation test for inherited breast cancer.Semantic proximity Read ↗

Mutational analysis of the neurofibromatosis type 1 gene in childhood myelodysplastic syndromes using a protein truncation assay.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.