Analysis of allelic variation of the TAP2 gene in sarcoidosis.

doi:10.1111/j.1399-0039.1997.tb02722.x

Back to search

Article

Analysis of allelic variation of the TAP2 gene in sarcoidosis.

Tissue antigens - 1 Feb 1997

Ishihara M, Ohno S, Ishida T, Naruse T, Kagiya M, Mizuki N, Maruya E, Saji H, Inoko H

Abstract excerpt

Sarcoidosis is a systemic granulomatous disease and the DRB1 gene of the DR subregion has been implicated for determining the genetic susceptibility to the disease. We evaluated the allelic variation of the TAP2 gene using the PCR-RFLP method as well as the mismatched PCR-RFLP method in 82 Japane...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters
Alleles
Female
Genetic Predisposition to Disease
Genetic Variation
HLA-D Antigens
Humans
Major Histocompatibility Complex
Male
Sarcoidosis

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.