Article
Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans.
Journal of molecular neuroscience : MN - 1 Feb 1997
Olde B, McCombie W R
Abstract excerpt
A cDNA encoding a serotonin receptor has been isolated from a Caenorhabditis elegans mixed stage cDNA library. The nematode serotonin receptor, designated 5HT-Ce, was permanently expressed in murine Ltk-cells, where it mediates adenylate cyclase attenuation. Sequence analysis and the pharmacological profiles demonstrate its relatedness not only to Drosophila and Lymnae 5HT receptors but also to mammalian 5HT1a...
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