Article
Pharmacological and genetic identification of serotonin receptor subtypes on Drosophila larval heart and aorta.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology - 1 Feb 2014
Majeed Zana R, Stacy Audra, Cooper Robin L
Abstract excerpt
Serotonin, 5-hydroxytryptamine (5-HT), plays various roles in the fruit fly, Drosophila melanogaster. Previous studies have shown that 5-HT modulates the heart rate in third instar larvae. However, the receptor subtypes that mediate 5-HT action in larval cardiac tissue had yet to be determined. In this study, various 5-HT agonists and antagonists were employed to determine which 5-HT receptor subtypes are...
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