Article
The angiotensin II type 1 receptor gene polymorphism is associated with coronary artery vasoconstriction.
Journal of the American College of Cardiology - 1 Mar 1997
Amant C, Hamon M, Bauters C, Richard F, Helbecque N, McFadden E P, Escudero X, Lablanche J M, Amouyel P, Bertrand M E
Abstract excerpt
OBJECTIVES: This study sought to assess the potential association of the angiotensin-converting enzyme (ACE) and angiotensin II type 1 (AT1) receptor gene polymorphisms on coronary vasomotion in humans. BACKGROUND: Abnormal coronary vasomotion plays a role in the clinical expression of coronary atherosclerosis. The components of the renin-angiotensin system are important determinants of vasomotor tone....
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