Article
Measurement of CD69 induction in the assessment of immune function in asymptomatic HIV-infected individuals.
Cytometry - 15 Feb 1997
Perfetto S P, Hickey T E, Blair P J, Maino V C, Wagner K F, Zhou S, Mayers D L, St Louis D, June C H, Siegel J N
Abstract excerpt
Peripheral blood mononuclear cells from many asymptomatic HIV-infected patients exhibit defects in cytokine production and impaired proliferative responses in vitro but the mechanisms underlying this subclinical immune deficiency are controversial. To determine whether abnormalities in the earliest events following receptor engagement may help to explain the in vitro immune dysfunction, we measured the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
