Article
Selective loss of T cell functions in different stages of HIV infection. Early loss of anti-CD3-induced T cell proliferation followed by decreased anti-CD3-induced cytotoxic T lymphocyte generation in AIDS-related complex and AIDS.
European journal of immunology - 1 May 1990
Gruters R A, Terpstra F G, De Jong R, Van Noesel C J, Van Lier R A, Miedema F
Abstract excerpt
To investigate the effects of persistant human immunodeficiency virus (HIV) infection on T cell reactivity, functional properties of peripheral blood T cells from HIV-seropositive homosexual men in various stages of infection were studied. T cell activation via CD3 resulting in proliferation and...
Topics
- AIDS-Related Complex
- Acquired Immunodeficiency Syndrome
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD28 Antigens
- CD3 Complex
- Cell Differentiation
- HIV Infections
- Humans
- Interleukin-2
- Lymphocyte Activation
- Male
- Phenotype