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Bone Morphogenetic Proteins Induce Differentiation in Astrocyte Lineage Cells

1 Jan 1994

Abstract excerpt

Serum-free mouse embryo (SFME) cells express Glial Fibrillary Acidic Protein (GFAP), a specific marker of the astrocyte lineage, when treated with either Transforming Growth Factor Beta (TGF-beta) or calf serum. We examined the effects of the related Bone Morphogenetic Proteins (BMPs) which are expressed in the developing murine nervous system. Treatment with the heterodimers BMP-2/6 and 2/7 followed by the...

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Identifiers

PMID: 7530466
DOI: 10.3109/08977199409015051

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Bone Morphogenetic Proteins Induce Differentiation in Astrocyte Lineage CellsPMID 7530466Read ↗

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