Article
Na+/H+-exchanger 3 activity and its gene in the spontaneously hypertensive rat kidney.
Journal of hypertension - 1 Jan 1997
Hayashi M, Yoshida T, Monkawa T, Yamaji Y, Sato S, Saruta T
Abstract excerpt
OBJECTIVE: To examine the mechanisms affecting proximal tubule sodium reabsorption, we studied the gene expression and functional changes of the Na+/H+-exchanger 3 (NHE3) and its gene expression in spontaneously hypertensive rats (SHR). METHODS: The S1 segment of the superficial proximal convoluted tubules (PCT) was microdissected from collagenase-treated kidneys of SHR and Wistar-Kyoto (WKY) rats. The tubules...
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