Article
Cloning of the cDNA encoding rat Presenilin-1.
Gene - 20 Feb 1997
Taniguchi T, Hashimoto T, Taniguchi R, Shimada K, Kawamata T, Yasuda M, Nakai M, Terashima A, Koizumi T, Maeda K, Tanaka C
Abstract excerpt
We isolated rat presenilin-1 (PS-1; also called S182 previously) cDNA from total brain RNA by using a reverse transcription-polymerase chain reaction (RT-PCR) technique with primers homologous to the conserved sequences of human and mouse PS-1. Rat PS-1 cDNA encoded 468 amino acids (aa) and the deduced aa sequence was highly homologous to those of the human (88.4%) and mouse (92.7%). Northern blot analysis of the...
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