Article
[The use of pluripotent mouse embryo stem cells for the production of chimeric animals].
Tsitologiia - 1 Jan 1996
Savchenkova I P, Fleischmann Z M, Bulla J, Brem G
Abstract excerpt
Embryonic stem (ES) cells derived from pluripotent cells of the early mouse embryos provide a powerful tool for genome manipulation in mammals. Conditions for maintaining and preservation of pluripotent properties of embryonic stem (ES) cells in culture using different tests are described. A simple aggregation of pluripotent ES cells with morulae-stage embryos for derivation of chimaeras is considered.
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