Article
[Genetic transformation of animals by the insertion of foreign genes into the zygotes].
Ontogenez - 1 Jan 2000
Serov O L
Abstract excerpt
A review of literature on genetic transformation of animal (mouse and Drosophila) germ cells by microinjection of the cloned genes into the pronuclei or into the early embryos. The fate of foreign genes and mechanisms of their integration into the recipient genome are considered in detail, as wel...
Topics
- Animals
- Chromosome Mapping
- Cloning, Molecular
- Crosses, Genetic
- DNA
- DNA, Recombinant
- DNA, Viral
- Drosophila melanogaster
- Female
- Gene Amplification
- Gene Expression Regulation
- Genes
- Genetic Engineering
- Genetic Variation
- Genetic Vectors
- Male
- Mice
- Mosaicism
