Article
Replacement of surgical vasectomy through the use of wild-type sterile hybrids.
Lab animal - 1 Feb 2021
Preece Chris, Alghadban Samy, Bouchareb Amine, Moralli Daniela, Biggs Daniel, Davies Benjamin
Abstract excerpt
For the production and rederivation of mouse strains, pseudopregnant female mice are used for embryo transfer and serve as surrogate mothers to support embryo development to term. Vasectomized males are commonly used to render pseudopregnancy in females, generated by surgical procedures associated with considerable pain and discomfort. Genetically modified mouse strains with a sterility phenotype provide a...
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