Article
Standardized peripheral blood mononuclear cell culture assay for zidovudine susceptibility testing of clinical human immunodeficiency virus type 1 isolates: effect of reducing the numbers of replicates and concentrations.
Journal of clinical microbiology - 1 Mar 1997
Marschner I C, Mayers D L, Erice A, Smeaton L, Johnson V A, Richman D D, Reichelderfer P, Japour A J
Abstract excerpt
Zidovudine susceptibility was assessed for 525 clinical human immunodeficiency virus type 1 isolates, before and after reducing the number of replicates and zidovudine concentrations in the standardized consensus peripheral blood mononuclear cell culture assay. We conclude that omitting the 0.001...
Topics
- Anti-HIV Agents
- Cells, Cultured
- Cost-Benefit Analysis
- Drug Resistance, Microbial
- Evaluation Studies as Topic
- HIV Infections
- HIV-1
- Humans
- Leukocytes, Mononuclear
- Microbial Sensitivity Tests
- Phenotype
- Virus Replication
- Zidovudine